BIOBANK of National Medical Research Center for Obstetrics Gynecology and Perinatology named after Academician V.I. Kulakov

Head of the Laboratory:  Natalya Mikhanoshina


Laboratory for collection and storage of biomaterial samples of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of the Ministry of Health of the Russian Federation was established in 2012. It works in close collaboration with the research laboratories and clinical Departments of the Center


  • Research:
    • The samples and collections are currently used for more than 20 research projects carried out by the Center and supported by several national foundations;
    • In the international collaborative projects with:
      • Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden;
      • Center for Research in Cancerology and Immunology Nantes-Angers, France;
      • Oxford Maternal & Perinatal Health Institute, Oxford, UK;
      • The Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands;
      • International Network on Cancer, Infertility and Pregnancy (INCIP);
      • European Surveillance of Congenital Anomalies (EUROCAT).
  • Validation of tests (on request on manufacturers) – e.g. kits for antibodies to COVID-19;
  • Development and validation of samples collection and storage protocols.



Development and validation of biomaterial samples collection and storage protocols, including the protocols based on the exclusion of the use of xenogenic materials for clinical vitrification.


More than 400,000 samples from patients with different obstetrical, gynecological and neonatal pathologies, including cervical, ovarian, breast and endometrial cancers, preeclampsia, gestational diabetes, habitual miscarriage, fetal growth restriction, chromosomal aberrations. Material: placenta, umbilical cord, amniotic fluid, fetal and embryonic tissues, biologic liquids, pathologic tissue samples, etc.

All samples are characterized in detail with patients’ demographic and clinical features, anonymized and bear a QR –code.

Biobank is integrated into the Center’s internal patients database Medialogue and therefore easily accessible for clinicians and researchers.



15 refrigerators with 32 400 storage units (~ 565,000 storage units). Storage conditions and monitoring comply with international standards (ISBER, BBMRI-ERIC). Laboratory is equipped with EBRO system – temperature and humidity monitoring in refrigeration systems and rooms.


Our Biobank is the member of the National Association of Russian biobanks (NASBio) and collaborates with Perinatal Centers in all regions of Russia and with leading biobanks abroad.